BDBM50402820 CHEMBL2208430

SMILES O[C@H](CNC(=O)c1c[nH]c2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=DIXSEWSBXAEKKY-OAHLLOKOSA-N

Data  2 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50402820   

TargetC-C chemokine receptor type 3(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50402820(CHEMBL2208430)Copy SMILESCopy InChI

Affinity DataKi:  2.51nMAssay Description:Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4- (methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetHistamine H1 receptor(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50402820(CHEMBL2208430)Copy SMILESCopy InChI

Affinity DataKi:  31.6nMAssay Description:Displacement of [3H]-pyrilamine from human histamine H1 receptor expressed in recombinant CHOK1 cells after 1 hrMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50402820(CHEMBL2208430)Copy SMILESCopy InChI

Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human ERG in HEK cells by ion flux electrophysiology assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL