BDBM50404154 CHEMBL5270908

SMILES COc1ccc(cc1)-c1cc2cc3c(cc2o1)occ(C=O)c3=O

InChI Key InChIKey=XAYKMQRPZRNJNL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50404154   

TargetCholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404154(CHEMBL5270908)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404154(CHEMBL5270908)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of LOX15 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404154(CHEMBL5270908)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404154(CHEMBL5270908)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human LOX5 using arachidonic acid preincubated for 10 mins followed by substrate addition by microplate spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404154(CHEMBL5270908)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of LOX5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed