BDBM50405267 CHEMBL5267954

SMILES CCOC1=CS(=O)(=O)c2cc3c(Nc4ccc5scnc5c4)ncnc3cc12

InChI Key InChIKey=DGOLQKDWHOHSFK-UHFFFAOYSA-N

Data  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50405267   

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50405267(CHEMBL5267954)
Affinity DataKd:  5.90nMAssay Description:Binding affinity to RIPK2 (unknown origin) assessed as dissociation constant by kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50405267(CHEMBL5267954)
Affinity DataKd:  43nMAssay Description:Binding affinity to RIPK3 (unknown origin) assessed as dissociation constant by kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50405267(CHEMBL5267954)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50405267(CHEMBL5267954)
Affinity DataKd: >3.00E+4nMAssay Description:Binding affinity to RIPK1 (unknown origin) assessed as dissociation constant by kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed