BDBM50405284 CHEMBL5272747

SMILES C=CC(=O)N1CCCCCCCCCn2cc(-c3ccnc(Nc4cccc1c4)n3)c1ccccc21

InChI Key InChIKey=JGSRURALHADGHE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50405284   

TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405284(CHEMBL5272747)
Affinity DataIC50: 13nMAssay Description:Inhibition of EGFR d746-750/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405284(CHEMBL5272747)
Affinity DataIC50: 25nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405284(CHEMBL5272747)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFR d746-750/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed