BDBM50405444 CHEMBL5285159

SMILES OC1CCN(CC1)c1ccc(NCc2cn(nn2)-c2cccc(NC(=O)c3cc(F)cc(F)c3)c2)cc1C(=O)N1CCCC1

InChI Key InChIKey=PEDODHFPRFORDN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50405444   

TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50405444(CHEMBL5285159)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of wild type ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50405444(CHEMBL5285159)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50405444(CHEMBL5285159)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50405444(CHEMBL5285159)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed