BDBM50405631 CHEMBL5286570

SMILES CN1CCN(CC1)C(C(=O)N1CCN(CC1)c1ncnc2[nH]cc(Br)c12)c1ccc(Cl)cc1

InChI Key InChIKey=MECMVUIPPJEYFL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50405631   

TargetRAC-alpha serine/threonine-protein kinase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405631(CHEMBL5286570)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of AKT1 (unknown origin) using Ser/Thr06 peptide substrate measured after 1 hr by FRET based Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405631(CHEMBL5286570)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of AKT3 (unknown origin) using Ser/Thr06 peptide substrate measured after 1 hr by FRET based Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50405631(CHEMBL5286570)
Affinity DataIC50: 20nMAssay Description:Inhibition of AKT2 (unknown origin) using Ser/Thr06 peptide substrate measured after 1 hr by FRET based Z-LYTE kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed