BDBM50405650 CHEMBL5271010

SMILES CN1CCN(CC1)c1ccc(Nc2cc3n(-c4ccc(CN)cc4)c(=O)cnc3cn2)nc1

InChI Key InChIKey=XKJRQOCKMSRCOH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50405650   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50405650(CHEMBL5271010)
Affinity DataIC50: 811nMAssay Description:Inhibition of human FLT3 D835Y mutant using TK peptide as substrate incubated for 1 hr in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50405650(CHEMBL5271010)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human wild type FLT3 using TK peptide as substrate incubated for 1 hr in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed