BDBM50406142 CHEMBL5280788

SMILES [H][C@]12CN(CCN1C(=O)C(C)C)Cc1cccc(NS(=O)(=O)CCCCC2)c1C

InChI Key InChIKey=GMUUZFVHYAPQEI-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50406142   

TargetNuclear receptor ROR-alpha(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50406142(CHEMBL5280788)
Affinity DataIC50: 2.50E+4nMAssay Description:Inverse agonist activity at 6His-tagged RORA LBD (unknown origin) expressed in Escherichia coli assessed as inhibition of biotinylated SRC1-2 derived...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetNuclear receptor ROR-beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50406142(CHEMBL5280788)
Affinity DataIC50: 2.50E+4nMAssay Description:Inverse agonist activity at 6His-tagged RORB LBD (unknown origin) expressed in Escherichia coli assessed as inhibition of biotinylated SRC1-2 derived...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
LigandPNGBDBM50406142(CHEMBL5280788)
Affinity DataKi:  3.70E+4nMAssay Description:Displacement of [3H]-dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed