BDBM50406161 CHEMBL5286601

SMILES C[C@@H](Nc1ncnc2n(C)c(=O)c(cc12)C1CCN(CC1)C(C)=O)c1cccc(c1)C(F)(F)CO

InChI Key InChIKey=QJZSCHYGDQYBHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406161   

TargetSon of sevenless homolog 1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50406161(CHEMBL5286601)
Affinity DataIC50: 73nMAssay Description:Inhibition of 6His-tagged SOS1 (unknown origin) mediated GST-tagged KRAS G12D activation preincubated for 15 mins followed by KRAS G12D addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed