BDBM50406168 CHEMBL5267612

SMILES CCn1c2ncnc(N[C@H](C)c3cc(N)cc(c3)C(F)(F)F)c2cc(C2CCN(CC2)C(C)=O)c1=O

InChI Key InChIKey=FJWIECNQTLEUJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406168   

TargetSon of sevenless homolog 1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50406168(CHEMBL5267612)
Affinity DataIC50: 91nMAssay Description:Inhibition of 6His-tagged SOS1 (unknown origin) mediated GST-tagged KRAS G12D activation preincubated for 15 mins followed by KRAS G12D addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed