BDBM50407400 CHEMBL5285855

SMILES C[C@@H](c1ccc(cc1)Cl)NC2=Nc3c(cnn3C4CCCC4)C(=O)N2

InChI Key InChIKey=FIUCLBJMUGCQTF-UHFFFAOYSA-N

Data  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50407400   

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50407400(CHEMBL5285855)
Affinity DataIC50: 11nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Rural Federal University of Rio De Janeiro

Curated by ChEMBL
LigandPNGBDBM50407400(CHEMBL5285855)
Affinity DataIC50: 11nMAssay Description:Inhibition of PDE9A (181 to 506 residues) (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50407400(CHEMBL5285855)
Affinity DataIC50: 366nMAssay Description:Inhibition of PDE5A1 (535 to 860 residues) (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50407400(CHEMBL5285855)
Affinity DataIC50: 554nMAssay Description:Inhibition of PDE1B2 (10 to 487 residues) (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed