BDBM50407965 CHEMBL3763870

SMILES COc1cccc2c1cc([nH]c2=O)-c1ccc(C)cc1

InChI Key InChIKey=RJVXWJADDFXFIL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50407965   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50407965(CHEMBL3763870)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human TNKS2 (873 to 1162 residues) measured after 15 hrs in presence of NAD+ by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50407965(CHEMBL3763870)
Affinity DataIC50: 30nMAssay Description:Inhibition of human TNKS1 (1030 to 1317 residues) measured after 20 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50407965(CHEMBL3763870)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PARP2 (unknown origin) using NAD as substrate incubated for 1 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50407965(CHEMBL3763870)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PARP1 incubated for 30 mins in the presence of NADMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed