BDBM50408825 CHEMBL5280147

SMILES Oc1c(Sc2ccccc2)cc(NS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)c2ccccc12

InChI Key InChIKey=ZXJHEANDHXHGMV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50408825   

TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408825BDBM50408825(CHEMBL5280147)
Affinity DataIC50: 700nMAssay Description:Binding affinity to STAT3 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408825BDBM50408825(CHEMBL5280147)
Affinity DataIC50: 800nMAssay Description:Inhibition of STAT3 phosphorylation in human Kasumi 1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408825BDBM50408825(CHEMBL5280147)
Affinity DataIC50: 800nMAssay Description:Inhibition of STAT3 phosphorylation in human HL-60 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408825BDBM50408825(CHEMBL5280147)
Affinity DataIC50: 800nMAssay Description:Inhibition of STAT3 phosphorylation in human MOLM-13 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed