BDBM50409191 CHEMBL365490

SMILES OC(=O)[C@H](Cc1ccccc1)Oc1ccc(cc1)-c1ccc(cc1)-c1c(Cc2ccccc2)oc2ccccc12

InChI Key InChIKey=CBAKPPAEHFOGJA-UMSFTDKQSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50409191   

TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50409191(CHEMBL365490)
Affinity DataIC50:  1.59E+4nMAssay Description:in vitro inhibitory activity against Dual specificity protein phosphatase 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50409191(CHEMBL365490)
Affinity DataIC50:  320nMAssay Description:In vitro inhibitory activity against human recombinant protein tyrosine phosphatase 1b (PTP1B)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50409191(CHEMBL365490)
Affinity DataIC50:  3.25E+3nMAssay Description:in vitro inhibitory activity against LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50409191(CHEMBL365490)
Affinity DataIC50:  3.23E+8nMAssay Description:Concentration required for 50% inhibition of tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50409191(CHEMBL365490)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of HEPTP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50409191(CHEMBL365490)
Affinity DataIC50:  322nMAssay Description:Inhibition of human recombinant PTP1B (1 to 321 residues) expressed in Escherichia coli using TRDIYETDYYRK as peptide substrate incubated for 30 mins...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50409191(CHEMBL365490)
Affinity DataIC50:  3.25E+3nMAssay Description:Inhibition of LAR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50409191(CHEMBL365490)
Affinity DataIC50:  3.37E+4nMAssay Description:Inhibition of PTPalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50409191(CHEMBL365490)
Affinity DataIC50:  1.59E+4nMAssay Description:Inhibition of VHR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50409191(CHEMBL365490)
Affinity DataIC50:  324nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed