BDBM50409487 CHEMBL2115165

SMILES CC1(C)OC[C@@H](O1)[C@@H](CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)N(O)C=O

InChI Key InChIKey=IVPPTWCRAFCOFJ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50409487   

TargetMatrix metalloproteinase-9(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50409487(CHEMBL2115165)
Affinity DataIC50: 0.5nMAssay Description:In vitro selective inhibition against Matrix metalloprotease-9 (MMP-9) using fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50409487(CHEMBL2115165)
Affinity DataIC50: 0.780nMAssay Description:In vitro selective inhibition against matrix metalloprotease-2 (MMP-2) using fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50409487(CHEMBL2115165)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Matrix metalloprotease-13 (MMP-13) in fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50409487(CHEMBL2115165)
Affinity DataIC50: 5nMAssay Description:Inhibition of Matrix metalloprotease-8 (MMP-8) in fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50409487(CHEMBL2115165)
Affinity DataIC50: 12nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3) in fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50409487(CHEMBL2115165)
Affinity DataIC50: 8.90E+3nMAssay Description:In vitro selective inhibition against matrix metalloprotease-1 (MMP-1) using a fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50409487(CHEMBL2115165)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Matrix metalloprotease-7 (MMP-7) in fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed