BDBM50411648 CHEMBL273165

SMILES CC(CCSc1nnc(-c2cccc3nc(C)ccc23)n1C)N1CCc2cc3nc(C)oc3c(Br)c2CC1

InChI Key InChIKey=DJHAFQLSNXBKIX-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50411648   

TargetD(3) dopamine receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411648(CHEMBL273165)
Affinity DataKi:  50.1nMAssay Description:Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411648(CHEMBL273165)
Affinity DataKi:  1.00E+3nMAssay Description:Antagonist activity at histamine H1 receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411648(CHEMBL273165)
Affinity DataKi: >1.58E+3nMAssay Description:Antagonist activity at dopamine D2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411648(CHEMBL273165)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]Dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed