BDBM50412144 CHEMBL494625

SMILES CCC12CC3CC(C1)CC(C3)(C2)C(=O)NNc1cccc2ncccc12

InChI Key InChIKey=RAJZQEGBKJYJIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50412144   

TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412144(CHEMBL494625)
Affinity DataIC50:  145nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50412144(CHEMBL494625)
Affinity DataIC50:  22.9nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed