BDBM50412446 CHEMBL484743

SMILES Cc1ccc2c(OCC3CCN(Cc4ccc5OCC(=O)Nc5c4)CC3)cccc2n1

InChI Key InChIKey=HKIASIHBZFIJOE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50412446   

TargetSodium-dependent serotonin transporter(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412446(CHEMBL484743)
Affinity DataKi:  31.6nMAssay Description:Inhibition of [3H]5HT reuptake at SERT in rat cortical synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412446(CHEMBL484743)
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [3H]5HT from human cloned 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412446(CHEMBL484743)
Affinity DataKi: >1.58E+3nMAssay Description:Displacement of [3H]5HT from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412446(CHEMBL484743)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]5HT from human cloned 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed