BDBM50412734 CHEMBL493079

SMILES O=C(NCc1cccc(c1)-c1cccc(CN2CCNCC2)c1)c1ccc2OCOc2c1

InChI Key InChIKey=WQMYHVQXLJIIHO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50412734   

TargetMuscarinic acetylcholine receptor M3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412734(CHEMBL493079)
Affinity DataIC50: 31.6nMAssay Description:Antagonist activity at human recombinant muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobili...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412734(CHEMBL493079)
Affinity DataIC50: 31.6nMAssay Description:Inhibition of human cloned muscarinic M3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412734(CHEMBL493079)
Affinity DataIC50: 158nMAssay Description:Inhibition of human cloned muscarinic M1 expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412734(CHEMBL493079)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human cloned muscarinic M2 receptor-Gqi5 chimeric protein expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed