BDBM50413049 CHEMBL4171849

SMILES OC(CNc1ccc(Cl)cc1C(=O)c1ccccc1)COc1cccc2[nH]c3ccccc3c12

InChI Key InChIKey=DUAJVUZPJOFVCI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413049   

TargetToll-like receptor 4(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50413049(CHEMBL4171849)
Affinity DataIC50: 2.11E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed