BDBM50416762 CHEMBL5288180

SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)C1SCCCS1

InChI Key InChIKey=MMUMATXYXOEJGR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50416762   

TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50416762(CHEMBL5288180)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of full length human FTO (1 to 505 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDNA oxidative demethylase ALKBH2(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50416762(CHEMBL5288180)
Affinity DataIC50:  4.27E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50416762(CHEMBL5288180)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of full length human FTO expressed in Escherichia coli BL21(DE3) rosetta by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRNA demethylase ALKBH5(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50416762(CHEMBL5288180)
Affinity DataIC50:  2.01E+5nMAssay Description:Inhibition of N-terminal truncated human ALKBH5 (66 to 292 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50416762(CHEMBL5288180)
Affinity DataIC50:  6.91E+4nMAssay Description:Inhibition of human ALKBH3 expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed