BDBM50417244 CHEMBL1271490

SMILES Cc1occc1-c1nnc(SCC(=O)Nc2ccc(C)c(C)c2)n1Cc1ccco1

InChI Key InChIKey=DYZZPJSEGPFOAX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50417244   

TargetOrexin receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417244(CHEMBL1271490)
Affinity DataKi:  2.51nMAssay Description:Antagonist activity against human orexin 2 receptor expressed in CHO cells assessed as effect in calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50417244(CHEMBL1271490)
Affinity DataKi:  631nMAssay Description:Antagonist activity against human orexin 1 receptor expressed in CHO cells assessed as effect in calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed