BDBM50417686 CHEMBL1233300

SMILES O=c2[nH]ccc3c(S(=O)(=O)N1CCCNCC1)cccc23

InChI Key InChIKey=ZAVGJDAFCZAWSZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50417686   

TargetRho-associated protein kinase 2(Human)
University of Dundee

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50417686BDBM50417686(CHEMBL1233300)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of His6-tagged ROCK2 (2 to 543 residues) (unknown origin) using peptide as substrate incubated for 15 mins in presence of ATP by immunoblo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
University of Dundee

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50417686BDBM50417686(CHEMBL1233300)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of GST-tagged LRRK2 G2019S mutant (1326 to 2527 residues) (unknown origin) using peptide as substrate incubated for 15 mins in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
University of Dundee

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50417686BDBM50417686(CHEMBL1233300)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of GST-tagged LRRK2 (1326 to 2527 residues) (unknown origin) using peptide as substrate incubated for 15 mins in presence of ATP by immuno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed