BDBM50418047 CHEMBL1688407::US10851083, Example 30::US11618744, Example 30

SMILES O=C(O)c1cnn(-c2nc3cc(C(F)(F)F)c(Cl)cc3[nH]2)c1

InChI Key InChIKey=UIQBWHCJBOIWNK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50418047   

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50418047BDBM50418047(CHEMBL1688407 | US10851083, Example 30 | US1161874...)
Affinity DataIC50: 72.4nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 50418047BDBM50418047(CHEMBL1688407 | US10851083, Example 30 | US1161874...)
Affinity DataIC50: 72.4nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent

TargetEgl nine homolog 1(Human)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50418047BDBM50418047(CHEMBL1688407 | US10851083, Example 30 | US1161874...)
Affinity DataIC50: 79.4nMAssay Description:Inhibition of PHD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed