BDBM50418602 CHEMBL1784168

SMILES Cc1c(F)cc(cc1-c1ccc(cc1)C(=O)NCC1CCCO1)C(=O)NC1CC1

InChI Key InChIKey=XSJJSPRQIAELIK-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50418602   

TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418602(CHEMBL1784168)
Affinity DataKi:  15.8nMAssay Description:Inhibition of GST-tagged p38alpha by fluorescence polarization methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418602(CHEMBL1784168)
Affinity DataIC50: 316nMAssay Description:Inhibition of p38alpha-dependent TNFalpha production in human whole blood preincubated for 1 hr before LPS challenge by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418602(CHEMBL1784168)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human CYP2C9 expressed in Escherichia coli by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed