BDBM50418877 CHEMBL1801456

SMILES CCn1c(CC(=O)NCc2cccc(Cl)c2C)c(C)nc1-c1ccc(F)cc1F

InChI Key InChIKey=QGGIEEFOSPUOQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50418877   

TargetP2X purinoceptor 7(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418877(CHEMBL1801456)
Affinity DataIC50: 39.8nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in HEK293 cells by ethidium bromide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418877(CHEMBL1801456)
Affinity DataIC50: 398nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in HEK293 cells by ethidium bromide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed