BDBM50420697 CHEMBL2087081

SMILES O=C(NOCC1CC1)c1ccc2[nH]ncc2c1Nc1ccc(I)cc1F

InChI Key InChIKey=DDHMFHZVMCWHNC-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50420697   

LigandChemical structure of BindingDB Monomer ID 50420697BDBM50420697(CHEMBL2087081)
Affinity DataEC50:  1.5nMAssay Description:Inhibition of MEK1-mediated ERK1 phosphorylation in human A375 cells after 2 hrs by immunoblotting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50420697BDBM50420697(CHEMBL2087081)
Affinity DataEC50:  1.5nMAssay Description:Inhibition of MEK1-mediated ERK1 phosphorylation in human HCT116 cells after 2 hrs by immunoblotting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50420697BDBM50420697(CHEMBL2087081)
Affinity DataIC50: 79nMAssay Description:Inhibition of MEK1-mediated ERK1 phosphorylation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed