BDBM50420808 CHEMBL2088041::CHEMBL2088042

SMILES CN(C)C(=O)C(CN1CCC2(CC1)OCCc1ccsc21)Cc1ccccc1Cl

InChI Key InChIKey=YWGYOBHYPGNKAP-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50420808   

TargetNociceptin receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420808(CHEMBL2088041 | CHEMBL2088042)
Affinity DataKi:  0.458nMAssay Description:Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420808(CHEMBL2088041 | CHEMBL2088042)
Affinity DataKi:  0.458nMAssay Description:Displacement of [3H]Nociceptin from human recombinant NOP receptor expressed in CHO cells by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420808(CHEMBL2088041 | CHEMBL2088042)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]Nociceptin from human recombinant NOP receptor expressed in CHO cells by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420808(CHEMBL2088041 | CHEMBL2088042)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420808(CHEMBL2088041 | CHEMBL2088042)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50420808(CHEMBL2088041 | CHEMBL2088042)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed