BDBM50421601 CHEMBL154298

SMILES C(Nc1ccccc1-c1ccccn1)C1=NCCN1

InChI Key InChIKey=GXGVZZFPDOETFM-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50421601   

TargetAlpha-1A adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421601(CHEMBL154298)
Affinity DataEC50:  6.80nMAssay Description:In vitro activation of human alpha-1A receptor expressed in rat-1 fibroblasts via calcium mobilization through the Gq coupled PLC pathway as function...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421601(CHEMBL154298)
Affinity DataEC50:  30nMAssay Description:In vitro activation of human Alpha-1B receptor expressed in rat-1 fibroblasts via calcium mobilization through the Gq coupled PLC pathway as function...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421601(CHEMBL154298)
Affinity DataIC50:  589nMAssay Description:In vitro binding affinity against human Alpha-1B adrenergic receptor expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421601(CHEMBL154298)
Affinity DataIC50:  117nMAssay Description:In vitro binding affinity against human Alpha-1D adrenergic receptor expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421601(CHEMBL154298)
Affinity DataIC50:  81nMAssay Description:In vitro binding affinity against human Alpha-1A adrenergic receptor expressed in rat-1 fibroblasts cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50421601(CHEMBL154298)
Affinity DataEC50:  42nMAssay Description:In vitro activation of human alpha-1D receptor expressed in rat-1 fibroblasts via calcium using mobilization through the Gq coupled PLC pathway as fu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed