BDBM50422381 CHEMBL384790

SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccc(CNCCCCCCNCCSSCCNCCCCCCNCc2ccc(cc2)C(=O)N2CCN(CC2)c2nc(N)c3cc(OC)c(OC)cc3n2)cc1

InChI Key InChIKey=IOEGVBQNHJRVBB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50422381   

TargetAlpha-1D adrenergic receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50422381(CHEMBL384790)
Affinity DataIC50: 25nMAssay Description:Antagonist affinity [non competitive (irreversible)] at alpha-1D-adrenoceptors on isolated thoracic aorta from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50422381(CHEMBL384790)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist affinity [non competitive (irreversible)] at alpha-1A-adrenoceptors on isolated prostatic Vas deferens from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50422381(CHEMBL384790)
Affinity DataIC50: 4.17E+4nMAssay Description:Antagonist affinity [non competitive (irreversible)] at alpha-1B-adrenoceptors on isolated spleen from ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed