BDBM504227 N-[6-(Azetidin-3-yloxy)-2- [(2R)-2-fluoro-3-hydroxy-3- methyl-butyl]-1-oxo-isoindolin- 5-yl]pyrazolo[1,5-a]pyrimidine- 3-carboxamide hydrochloride::US11034698, Example 73

SMILES CC(C)(O)[C@H](F)CN1Cc2cc(NC(=O)c3cnn4cccnc34)c(OC3CNC3)cc2C1=O

InChI Key InChIKey=BJZUXWCBMOLYGD-LJQANCHMSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504227   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM504227(N-[6-(Azetidin-3-yloxy)-2- [(2R)-2-fluoro-3-hydrox...)
Affinity DataKi:  3.70nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent