BDBM504241 (R)-N-(6-(tert-Butoxy)-2-(2- fluoro-3-hydroxy-3- methylbutyl)-1-oxoisoindolin-5- yl)pyrazolo[1,5-a]pyrimidine-3- carboxamide::US11034698, Example 90

SMILES CC(C)(C)Oc1cc2C(=O)N(C[C@@H](F)C(C)(C)O)Cc2cc1NC(=O)c1cnn2cccnc12

InChI Key InChIKey=INSRRINIOXIHKN-LJQANCHMSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504241   

TargetNuclear receptor ROR-gamma(Human)
Genentech

US Patent
LigandPNGBDBM504241((R)-N-(6-(tert-Butoxy)-2-(2- fluoro-3-hydroxy-3- m...)
Affinity DataKi:  0.610nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent