BDBM50424566 CHEMBL2312508

SMILES Cc1ncccc1Oc1ncnc(N2C3CC4CC2CC(C3)N4C(=O)OC(C)(C)C)c1F

InChI Key InChIKey=WUCDOWYHHGDYTF-UHFFFAOYSA-N

Data  1 KI  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424566   

TargetGlucose-dependent insulinotropic receptor(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50424566(CHEMBL2312508)Copy SMILESCopy InChI

Affinity DataKi:  814nMAssay Description:Binding affinity to human GPR119 in HEK293FT cell membrane by radioligand binding assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetGlucose-dependent insulinotropic receptor(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50424566(CHEMBL2312508)Copy SMILESCopy InChI

Affinity DataEC50: >3.01E+3nMAssay Description:Agonist activity at human GPR119 in HEK293 cells assessed as cAMP accumulation after 30 mins by CRE-beta-lactamase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL