BDBM50424576 CHEMBL2312158

SMILES Cc1c(Oc2ccc(cc2F)-n2cnnn2)ncnc1N1C2CC3CC1CC(C2)N3C(=O)OC1(C)CC1

InChI Key InChIKey=KIAOXWICDUNQFO-UHFFFAOYSA-N

Data  1 KI  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424576   

TargetGlucose-dependent insulinotropic receptor(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50424576(CHEMBL2312158)Copy SMILESCopy InChI

Affinity DataKi:  15nMAssay Description:Binding affinity to human GPR119 in HEK293FT cell membrane by radioligand binding assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
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TargetGlucose-dependent insulinotropic receptor(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50424576(CHEMBL2312158)Copy SMILESCopy InChI

Affinity DataEC50:  22nMAssay Description:Agonist activity at human GPR119 in HEK293 cells assessed as cAMP accumulation after 30 mins by CRE-beta-lactamase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL