BDBM50424822 CHEMBL2315111

SMILES Cc1cnc(CNC(=O)c2ccc(nn2)N2CCN(CC2)C(=O)c2ccccc2C(F)(F)F)cn1

InChI Key InChIKey=JSKCBBJNQMKSTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424822   

TargetAcyl-CoA desaturase 1(Mouse)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424822(CHEMBL2315111)
Affinity DataIC50: 33nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50424822(CHEMBL2315111)
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed