BDBM50424987 CHEMBL2311774

SMILES O=C(CCC(=O)N1CCCN(CC1)C1(C(=O)NC(=O)NC1=O)c1ccc(Oc2ccccc2)cc1)N1CCCN(CC1)C1(C(=O)NC(=O)NC1=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=PHKLGXHLOXCURO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50424987   

TargetCollagenase 3(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50424987(CHEMBL2311774)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant MMP-13 after 45 mins by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50424987(CHEMBL2311774)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant MMP-8 after 45 mins by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50424987(CHEMBL2311774)
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant MMP-2 after 45 mins by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50424987(CHEMBL2311774)
Affinity DataIC50: 85nMAssay Description:Inhibition of human recombinant MMP-9 after 45 mins by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed