BDBM50425013 CHEMBL2312214

SMILES Oc1c(CN(CC#N)Cc2ccccc2)cc([N+]([O-])=O)c2cccnc12

InChI Key InChIKey=CJFJGNGFFLNDIH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50425013   

TargetCathepsin B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50425013(CHEMBL2312214)
Affinity DataKi:  8.00E+3nMAssay Description:Mixed inhibition of human recombinant cathepsin B exopeptidase activity using Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH substrate assessed as inhibition co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50425013(CHEMBL2312214)
Affinity DataKi:  1.90E+4nMAssay Description:Uncompetitive inhibition of human recombinant cathepsin B endopeptidase activity using Z-Arg-Arg-AMC substrate assessed as inhibition constant for en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50425013(CHEMBL2312214)
Affinity DataKi:  7.90E+4nMAssay Description:Mixed inhibition of human recombinant cathepsin B exopeptidase activity using Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH substrate assessed as inhibition co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed