BDBM50425047 CHEMBL2312570::US9402842, 22

SMILES COC(=O)C(=O)Nc1ccc2c3C(=O)c4ccccc4-c3n(CCCN)c(=O)c2c1

InChI Key InChIKey=CGKWENCMZIHWAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425047   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM50425047(CHEMBL2312570 | US9402842, 22)
Affinity DataIC50: 4.50E+4nMpH: 7.5 T: 2°CAssay Description:A 5′-[32P]-labeled single-stranded DNA oligonucleotide containing a 3′-phosphotyrosine (N14Y) was generated as described by Dexheimer et ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
US Patent

TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM50425047(CHEMBL2312570 | US9402842, 22)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed