BDBM50425132 CHEMBL2313258
SMILES Cc1nc2ccc(cc2n2c(nnc12)-c1ccccc1Cl)C(=O)NCc1ccccc1
InChI Key InChIKey=LPZCANRRYYLKAQ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50425132
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen-Cilag
Curated by ChEMBL
Janssen-Cilag
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of rat PDE10A expressed in Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen-Cilag
Curated by ChEMBL
Janssen-Cilag
Curated by ChEMBL
Affinity DataIC50: 0.380nMAssay Description:Inhibition of human recombinant PDE2A expressed in Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Janssen-Cilag
Curated by ChEMBL
Janssen-Cilag
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair