BDBM50425145 CHEMBL2311556

SMILES CCOC(=O)c1ccc2nc(C)c3nnc(-c4ccccc4Cl)n3c2c1

InChI Key InChIKey=MKNKYIBULNNKQR-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50425145   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Janssen-Cilag

Curated by ChEMBL

LigandBDBM50425145(CHEMBL2311556)Copy SMILESCopy InChI

Affinity DataIC50:  33nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen-Cilag

Curated by ChEMBL

LigandBDBM50425145(CHEMBL2311556)Copy SMILESCopy InChI

Affinity DataIC50:  35nMAssay Description:Inhibition of rat PDE10A expressed in Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Janssen-Cilag

Curated by ChEMBL

LigandBDBM50425145(CHEMBL2311556)Copy SMILESCopy InChI

Affinity DataIC50:  4.40nMAssay Description:Inhibition of human recombinant PDE2A expressed in Sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI