BDBM50425661 CHEMBL2315240
SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2Cc3cccc(NC(=O)CN4CCN(CC4)CC(=O)Nc4cccc(C[C@@H](NS(=O)(=O)Cc5ccccc5)C(=O)N2)c4)c3)cc1
InChI Key InChIKey=OXHLIVRHOPCUSV-MPQUPPDSSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50425661
Affinity DataKi: 3.20nMAssay Description:Inhibition of human plasma kallikrein using H-D-Pro-Phe-Arg-pNA as substrate after 5 to 10 mins by micro plate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of pig trypsin using CH3SO2-D-Cha-Gly-Arg-pNA as substrate after 5 to 10 mins by micro plate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of human plasmin protease domain using Tos-Gly-Pro-Lys-pNA as substrate by micro plate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human factor Xa using CH3OCO-D-Cha-Gly-Arg-pNA as substrate after 5 to 10 mins by micro plate reader analysisMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Philipps University Marburg
Curated by ChEMBL
Philipps University Marburg
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Inhibition of human activated protein C using H-D-Lys(Cbz)-Pro-Arg-pNA as substrate after 5 to 10 mins by micro plate reader analysisMore data for this Ligand-Target Pair
Affinity DataKi: 227nMAssay Description:Inhibition of human thrombin using CH3SO2-D-Cha-Gly-Arg-pNA as substrate after 5 to 10 mins by micro plate reader analysisMore data for this Ligand-Target Pair