BDBM50425670 CHEMBL2315561
SMILES CN(c1ncccc1CNc1c(Br)cnc2nc([nH]c12)-c1ccc(F)cc1)S(C)(=O)=O
InChI Key InChIKey=PBCVYFSFCFGZOT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50425670
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated His-TEV-hsFAK(31-686)(K454R) substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as phosphorylation at tyrosine 397 after 45 minsMore data for this Ligand-Target Pair
Affinity DataKd: 335nMAssay Description:Binding affinity to FAK (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair