BDBM50425708 CHEMBL2316211

SMILES O=C(CNc1nccc2ncc(C(F)(F)F)cc12)NC1CN([C@H]2CC[C@@](O)(c3cncs3)CC2)C1

InChI Key InChIKey=SMYCACLLALUJTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425708   

TargetC-C chemokine receptor type 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425708BDBM50425708(CHEMBL2316211)
Affinity DataIC50: 38nMAssay Description:Antagonist activity against human CCR2 in human THP1 cells using [I125]MCP-1 by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425708BDBM50425708(CHEMBL2316211)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human ERG assessed as [3H]astemizole binding activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed