BDBM50426345 CHEMBL2326686

SMILES Fc1ccc(cc1Cl)C1CNCC=CC1

InChI Key InChIKey=PTKQUPHPZRJQRH-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50426345   

TargetSodium-dependent dopamine transporter(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50426345(CHEMBL2326686)
Affinity DataKi:  68nMAssay Description:Inhibition of human recombinant DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50426345(CHEMBL2326686)
Affinity DataKi:  130nMAssay Description:Inhibition of human recombinant NET expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50426345(CHEMBL2326686)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human recombinant SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50426345(CHEMBL2326686)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50426345(CHEMBL2326686)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed