BDBM50426490 CHEMBL2323288

SMILES CC(C)[C@@H]1NC(=O)Cn2nnnc2-c2csc(CNC(=O)C[C@H](OC1=O)\C=C\CCS)n2

InChI Key InChIKey=XWMICCNJUKWEMB-YCBCECCRSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50426490   

TargetHistone deacetylase 9(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50426490(CHEMBL2323288)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of C-terminal His-tagged human recombinant HDAC9 (amino acids 604- 1066) expressed in baculovirus expression system using fluorogenic acet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50426490(CHEMBL2323288)
Affinity DataIC50:  1.67E+3nMAssay Description:Inhibition of C-terminal His-tagged and C-terminal FLAG-tagged full length human recombinant HDAC1 expressed in baculovirus expression system using f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50426490(CHEMBL2323288)
Affinity DataIC50:  3.27E+3nMAssay Description:Inhibition of C-terminal His-tagged full length human recombinant HDAC2 expressed in baculovirus expression system using fluorogenic acetylated pepti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50426490(CHEMBL2323288)
Affinity DataIC50:  649nMAssay Description:Inhibition of C-terminal His-tagged full length human recombinant HDAC3 co-expressed with NcoR2 in baculovirus expression system using fluorogenic ac...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed