BDBM50427365 CHEMBL2326000

SMILES CC(C)[C@@](C)(O)[C@@H]1CN(CCN1)c1nc(-c2n[nH]c3ncccc23)c(F)cc1CO

InChI Key InChIKey=ZWFTUJOJJZSCMP-HRAATJIYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50427365   

TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50427365(CHEMBL2326000)
Affinity DataKi:  0.100nMAssay Description:Inhibition of full-length recombinant PKC theta (unknown origin) using ERMRPRKRQGSVRRRV as substrate after 60 mins by scintillation counting analysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein kinase C delta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50427365(CHEMBL2326000)
Affinity DataKi: <10nMAssay Description:Inhibition of PKC delta (unknown origin) using ERMRPRKRQGSVRRRV as substrate after 15 mins by spectrophotometry in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein kinase C alpha type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50427365(CHEMBL2326000)
Affinity DataKi:  205nMAssay Description:Inhibition of PKC alpha (unknown origin) using RRRRRKGSFKRKA as substrate after 15 mins by spectrophotometry in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProtein kinase C theta type(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50427365(CHEMBL2326000)
Affinity DataIC50:  1nMAssay Description:Inhibition of full-length recombinant PKC theta (unknown origin) using ERMRPRKRQGSVRRRV as substrate after 60 mins by scintillation counting analysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed