BDBM50427485 CHEMBL2326959::US10308662, Compound 120::US9505780, 120
SMILES O=C(Nc1ccc(cc1)-c1csc2c1oc(cc2=O)N1CCOCC1)c1ccncc1
InChI Key InChIKey=OTKBOMOGNAEETG-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50427485
Affinity DataIC50: 326nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
Affinity DataIC50: 393nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Signal Rx Pharmaceuticals
US Patent
Signal Rx Pharmaceuticals
US Patent
Affinity DataIC50: 95nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Signal Rx Pharmaceuticals
US Patent
Signal Rx Pharmaceuticals
US Patent
Affinity DataIC50: 21nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Signal Rx Pharmaceuticals
US Patent
Signal Rx Pharmaceuticals
US Patent
Affinity DataIC50: 556nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Signal Rx Pharmaceuticals
US Patent
Signal Rx Pharmaceuticals
US Patent
Affinity DataIC50: 556nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
Affinity DataIC50: 326nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
Affinity DataIC50: 393nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Signal Rx Pharmaceuticals
US Patent
Signal Rx Pharmaceuticals
US Patent
Affinity DataIC50: 95nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Signal Rx Pharmaceuticals
US Patent
Signal Rx Pharmaceuticals
US Patent
Affinity DataIC50: 21nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Signal Rx Pharmaceuticals
US Patent
Signal Rx Pharmaceuticals
US Patent
Affinity DataIC50: 14nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair