BDBM50428449 CHEMBL449451

SMILES COc1ccc(cc1F)-c1ccc(O)c(CN=O)c1

InChI Key InChIKey=PMSZIRMXQHNMQO-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50428449   

TargetCarbonic anhydrase 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50428449(CHEMBL449451)
Affinity DataKi:  3.66E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 12(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50428449(CHEMBL449451)
Affinity DataKi:  5.94E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50428449(CHEMBL449451)
Affinity DataKi:  6.93E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50428449(CHEMBL449451)
Affinity DataKi:  1.02E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50428449(CHEMBL449451)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of GLUT1 in human H1299 cells assessed as inhibition of 2-deoxy-D-[3H]-glucose uptake incubated for 15 mins prior to 2-deoxy-D-[3H]-glucos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed