BDBM50428686 CHEMBL2332701

SMILES COC1CN(C[C@@H]2CC[C@@H](CO[C@H]3CC[C@@H](CC3)C(O)=O)N2C(=O)Cc2ccc3nc(Nc4cc(F)ccc4C)oc3c2F)C1

InChI Key InChIKey=FBHNELKHWDCBOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50428686   

TargetIntegrin alpha-4/beta-1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50428686(CHEMBL2332701)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of Europium-labeled human VCAM1 binding to human VLA4 expressed in Chinese hamster 4B4 cells incubated for 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50428686(CHEMBL2332701)
Affinity DataIC50: 35nMAssay Description:Inhibition of Europium-labeled human VCAM1 binding to human VLA4 expressed in Chinese hamster 4B4 cells incubated for 60 mins in presence of 3% HSA b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed