BDBM50428971 CHEMBL2333224

SMILES COc1ccc(CNc2c(CO)cnc3c(cc(cc23)C#N)N2CCOCC2)cc1Cl

InChI Key InChIKey=AOSQOVNSDOMLNJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50428971   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50428971(CHEMBL2333224)
Affinity DataIC50: 0.630nMAssay Description:Inhibition of PDE5 (unknown origin) using FAM-cGMP as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed